Trifexis For Dogs 60.1-120lbs 6 Month

List Price: $199.99
Sale Price: $148.85
Code: tri120-6pk
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Trifexis is a monthly chewable tablet for dogs that protects against certain parasites. This preventative provides protection against dangerous parasites such as fleas, heartworms, hookworms, roundworms, and whipworms. It combines two trusted active ingredients, spinosad and milbemycin oxime. Spinosad works by activating receptors in the flea nervous system, causing them to die. Milbemycin oxime acts by disrupting the nerve transmission within heartworms, leading to their death.


Dogs (8+ weeks of age, weighing 5+ lbs)


  • Begins killing biting fleas within 30 minutes
  • Kills fleas before they can lay eggs
  • Prevents heartworm disease
  • Treats and controls roundworms, hookworms, and whipworms
  • Artificial beef flavor made from pork liver and hydrolyzed soy
  • Easy-to-administer chewable tablet

How it works:

Spinosad, an active ingredient in Trifexis, starts to work within 30 minutes to kill fleas and has been proven to kill 100% of all biting fleas within 4 hours. Trifexis also kills flea eggs before they can mature, which helps to end the flea life cycle. Trifexis prevents heartworm disease by killing microfilariae and larvae from maturing into adult heartworms.


Store at controlled room temperature 68-77°F (20-25°C).

Trifexis does not protect against ticks.
Weight range (lbs) Weight range (kg) Dosage
5-10lbs 2.3-4.5kg 1 tablet (Pink box)
10.1-20lbs 4.5-9kg 1 tablet (Orange box)
20.1-40lbs 9.1-18.1kg 1 tablet (Green box)
40.1-60lbs 18.2-27.2kg 1 tablet (Blue box)
60.1-120lbs 27.2-54.4kg 1 tablet (Brown box)
Over 120lbs Over 54.4kg Combination of chewables based on weight


  • Keep out of reach of children and pets.
  • Trifexis is not intended for human use. It is for use in dogs only.
  • Do not use this medication in dogs younger than 8 weeks or less than 5 pound
  • Trifexis may interact with some other medications. Therefore, inform your veterinarian of any and all medications your pet may be taking.
  • Do not use this medication with products containing ivermectin.

Possible side effects:

Adverse reactions and serious side effects are rare, however, they can occur. In the case of a more serious side reaction, seek immediate veterinary attention. Serious reactions include vomiting, depression/lethargy, diarrhea, shaking, seizures, uncontrollable body movements, or unusual salivation.

Note: In clinical trials adverse reactions included: vomiting, pruritus, lethargy, and diarrhea