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Staphage Lysate (SPL) 10 mL Vial

Staphage Lysate (SPL) 10 mL Vial
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List Price: $189.99
Sale Price: $151.99
Code: staph10
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Refrigerated item
Requires Overnight Shipping

Product Info:

Staphage Lysate (SPL) (Staphylococcus aureus phage lysate) is a bacteriologically sterile staphylococcal vaccine containing the components of S. aureus, a bacteriophage, and some culture medium ingredients (sodium chloride and ultrafiltered beef heart infusion broth) in solution. It is indicated for the treatment of canine pyoderma and related staphylococcal hypersensitivity, or polymicrobial skin infections with a staphylococcal component.

Adverse Reactions:

SPL may cause general vaccine-type reactions (i.e., malaise, fever, and/or chills). If excessive, these reactions may be lessened by dose reduction. Transient reactions at the site of injection (i.e., redness, itching, andlor swelling) may occur in 2 to 3 hours and may last up to 3 days, steadily decreasing. If excessive, these reactions may be lessened by dose reduction.

Allergic Reactions:

Although the chance of allergic reactions is very small, the patient should be observed for 45 minutes to 1 hour for immediate and for 48 hours for delayed reactions. Allergic reactions you might observe include weakness, vomiting, diarrhea, severe itching, and fast breathing. For chronic, recurrent, refractory, or deep-seated infections, it may be necessary to increase cautiously the frequency and/or the dose to achieve the desired therapeutic response.

Dosage and Administration:

SPL is administered by subcutaneous injection. The severity of the infection and the response of the patient should be the guiding factors in adjusting the dosage regimen. All highly allergic patients (or those predisposed to allergy) should first be skin-tested to assess their relative sensitivity to SPL. Following the initial injection, subsequent injections should avoid previous injection sites. If an undue amount of local redness, itching, and/or swelling ensues, await a partial subsidence of the reactions, proceed with '/2 the previous dose, and make incremental increases at longer intervals.