Mexiletine HCl 150mg PER CAPSULE

Mexiletine HCl 150mg PER CAPSULE
List Price: $1.19
Sale Price: $0.52
Code: mexiletine-150-caps
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Product Info:

Mexiletine is a class 1B, sodium channel blocker, anti-arrhythmia drug which is used to treat chronic ventricular arrhythmias in dogs. The mechanism of action is similar to lidocaine. Mexiletine is used to treat ventricular arrhythmias including PVC’s and ventricular tachycardia. If an animal has responded well to lidocaine during an acute episode, it is likely to respond well to mexiletine.




  • Treats ventricular arrhythmias in dogs
  • Used to treat ventricular arrhythmias including PVC's and ventricular tachycardia
  • Similar to lidocaine
  • Mexiletine may be combined with either atenolol or sotalol in instances when monotherapy is not adequate.
  • A positive response to therapy would be an 85% reduction of ventricular premature contractions.
  • Mexiletine may be used to treat inherited cardiomyopathy in Boxers and dilated cardiomyopathy in Doberman pinschers.

How it works:

Mexiletine is well absorbed orally and has a bioavailability of approximately 85%. It is primarily excreted in the urine although approximately 10% is metabolized by the liver and excreted in the feces. The half-life of this drug may be prolonged in animals with reduced cardiac output, or after an acute myocardial infarction. The half-life may also be prolonged in animals with hepatic dysfunction or severe kidney disease.


Should be stored at room temperature, away from moisture and heat.

How to Use:

Pet Weitht Dosage
Dogs All weights Use as directed by your veterinarian.
Cats All weights Use as directed by your veterinarian.

Side Effects:

The most common side effects are related to the GI tract including nausea and vomiting. Giving food with mexiletine has been shown to decrease the incidence of GI side effects. Other possible side effects include central nervous system signs such as dizziness, loss of balance and trembling, shortness of breath, and cardiac signs including PVCs or chest pain.