Tri-Heart Plus For Dogs 51-100lbs 6 Month

List Price: $69.99
Sale Price: $46.99
Code: tribrwn
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Tri-Heart Plus is a heartworm preventative. This medication prevents infestation by heartworms, roundworms, and hookworms. It contains two active ingredients, ivermectin and pyrantel pamoate. These are the same active ingredients found in Heartgard® Plus.

All dogs should be tested for heartworm infection before starting a preventative program.


Dogs (6+ weeks of age, no weight requirement)


  • Tasty beef-flavored chewable tablets
  • Easy to administer
  • Small, easy-to-chew tablet for smaller or finicky dogs
  • Given once a month

How it works:

Ivermectin/Pyrantel is an anthelmintic (dewormer). The ingredient pyrantel pamoate is used to treat and control roundworms and hookworms in dogs. Together, these ingredients cause neurological damage to parasites. This leads to the paralysis and death of heartworms, roundworms, and hookworms.

Studies have indicated that certain dogs of the herding breeds are more sensitive to the effects of ivermectin administered at elevated dose levels due to the MDR1 gene. Dog breeds that may be affected include:

  • Australian Shepherd
  • Australian Shepherd Mini
  • Border Collie
  • Collie
  • English Shepherd


Should be stored at room temperature.

Do not remove the chewable from its wrapper until ready to give to your pet.

  • Give Tri-Heart Plus (Ivermectin/Pyrantel) Flavored Chewables once a month on the same day of each month year-round.
  • Tri-Heart Plus (Ivermectin/Pyrantel) Flavored Chewables can be given by hand, mixed intact with a small amount of food, or placed in the back of your dog's mouth for forced swallowing.
  • Watch your dog closely following dosing to be sure the entire dose has been swallowed. If it is not completely swallowed, give one more full recommended dose as soon as possible.
Weight range (lbs) Weight range (kg) Dosage
Up to 25lbs Up to 11.4kg 1 chewable every month (Blue Box)
26-50lbs 11.8-22.6kg 1 chewable every month (Green Box)
51-100bs 23-45.3kg 1 chewable every month (Brown Box)
Over 100lbs Over 45.3kg Combination of chewables based on weight


All dogs should be tested for heartworm infection before starting a preventative program.

  • Can cause sensitivities in the following herding dog breeds: Australian Shepherd, Australian Shepherd Mini, Border Collie, Collie and English Shepherd.
  • The safe use of this drug has not been evaluated in pregnant or lactating dogs.
  • For use in dogs only.
  • Store Tri-Heart Plus (Ivermectin/Pyrantel) at room temperature.
  • Do not remove the tablet from its wrapper until ready to give to your pet.
  • Keep this medication away from children and pets.

Possible side effects:

Adverse reactions and serious side effects are rare, however, they can occur. In the case of a more serious side reaction, seek immediate veterinary attention. Serious reactions include vomiting, depression/lethargy, diarrhea, shaking, seizures, uncontrollable body movements, or unusual salivation.