Advantage® II combines the properties of the original formulations of Advantage® Topical Solution, with the insect growth regulator (IGR) pyriproxyfen, which inhibits the development of flea eggs and kills flea larvae.
Pyriproxyfen, the added compound Advantage® II, interferes with the hormone signaling of growing insects so that fleas in immature stages are unable to mature. The hormone pathway that pyriproxyfen targets is specific to insects and does not affect mammals.
Advantage® II starts killing fleas in an hour. Within 12 hours of initial application, 98-100 percent of all existing fleas on pets are dead. Advantage® II is for kittens 8 weeks of age and older. For fast relief for your pet, see your veterinarian and ask for Advantage® II flea control.